Scottish architect and engineer. Son of Thomas Mylne, a deacon. Married (1770) to Mary Home (d. 1797) with whom he had nine children. Ca. 1753-1758 he studied architecture in Rome, at least some of the time together with his brother James.1

Following his arrival back in London in 1759 he became a much respected architect and builder/renovator of such grand projects as Blackfriar's Bridge in London, St Cecilia's Hall in Edinburgh, The Hunterian Medical School in London, Inveraray village and castle in Scotland, Greenwich Hospital, Rochester Cathedral and even the Gloucester and Sharpness Canal. He died in 1811 and was buried in St. Paul's Cathedral.