Daughter of Rene de Vicq (1683-1737) and Maria Jacoba van Goor (1687-1737). Married (1739) to Diederik Jacob van Tuyll van Serooskerken. Mother of Belle de Zuylen.
Boswell first mentions "cultivating her acquaintance" on December 16, 1763.1
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On his Grand Tour of Europe in 1764-1765, Boswell visited and befriended the famous philosophers Jean-Jacques Rosseau and François-Marie Arouet (Voltaire), and back in Edinburgh he was a personal friend of David Hume.